{"id":155,"date":"2018-04-23T10:00:06","date_gmt":"2018-04-23T10:00:06","guid":{"rendered":"http:\/\/fnfdoc.com\/?p=155"},"modified":"2018-06-22T20:42:44","modified_gmt":"2018-06-22T20:42:44","slug":"lupus-affects-health","status":"publish","type":"post","link":"https:\/\/fnfdoc.com\/lupus-affects-health\/","title":{"rendered":"How Lupus Affects The Health?"},"content":{"rendered":"

Brief Introduction To Lupus<\/h2>\n

Systemic Lupus Erythematosus (SLE), commonly known as Lupus, is a group of complex hard-to-diagnose autoimmune disorders with 1.5 million cases reported each year in America. It covers a wide variety of related diseases. This article focuses on SLE which is known to the common man as Lupus (Lt. wolf <\/em>due to the rash that resembles wolf bite).<\/p>\n

\"Lupus\"
Lupus<\/figcaption><\/figure>\n

Lupus is a chronic, inflammatory disease that presents in a kaleidoscopic manner, with periods of extreme sickness alternating with milder times. This fluctuating nature of Lupus makes it hard to identify. And thus, patients suffer unnecessarily and agonizingly for years and years. The illness is more common among women of child-bearing age due to the presence of female sex hormones. Even more tricky is the fact that its cause is unknown and not well-defined.<\/p>\n

Causes<\/h2>\n

The causes of Lupus are not clearly outlined as with some other disorders like polio or thalassemia. One may have the disease as a result of genetic and environmental <\/strong>factors.\u00a0 Vitamin D Deficiency<\/em><\/strong><\/span><\/a> is also a notable causal agency. Smoking may also be a causative agent.<\/p>\n

Genetics:<\/h3>\n

The disease is inheritable and commoner in families of certain ethnicities and gene linkages. A specific gene for Lupus has not been identified but some of the genes responsible are HLA Class I and Class II, BANK1, STAT4, and BLK. The etiology of this disease suggests that it runs in families and a has a heritability rate of >66%. Among identical twins, there is a 24% chance of susceptibility for one if the other has already been diagnosed.<\/p>\n

Environment:<\/h3>\n

The fact that Lupus is more common among people of certain social and geographic backgrounds hints at the role of the atmosphere in its development.<\/p>\n

Drug Side Effects:<\/h3>\n

Drug-induced Lupus is a curable condition that occurs in patients with other chronic, long-term diseases. The drugs that increase the risk are hydralazine, procainamide, quinidine, and phenytoin.<\/p>\n

Photosensitivity:<\/h3>\n

Some people are hypersensitive to sources of UV<\/a> light like the Sun, halogen lights, discharge lamps, and lasers.\u00a0 This condition is called photosensitivity. It reportedly causes many symptoms associated with SLE<\/a> like joint pain, fatigue, fever, and rashes.<\/p>\n

Mechanism<\/h2>\n

Our immune system fights against foreign organisms, microbes and germs. It is the defense system of the body. In Lupus, this security service receives flawed intelligence and starts producing autoantibodies (think Army personnel) against the body’s own tissues. The situation is aggravated by the multiple numbers of organs that face the wrath of a crazy immune system. It involves the production of antinuclear antibodies which inflame the organs and cripple the joints. The appearance of symptoms appears in two phases designated as Flares <\/em><\/strong>and Remission<\/em><\/strong>. A flare is that length of time for which the disease is in full swing and the symptoms are clearly visible. By remission, we mean the interval in between in which the disease is intermediate and tolerable.<\/p>\n

Signs And Symptoms<\/h2>\n
\"Lupus
Lupus Symptoms<\/figcaption><\/figure>\n

Lupus presents in a changing and relapsing manner. The symptoms may be intense for a few days or weeks and then completely disappear, only to return a few months later.<\/p>\n

This moody nature of the Wolf <\/em>makes it hard to tame. It baffles the most sharp-witted of clinicians and adds to the patient’s misery. However, the clear indicators of Lupus are:<\/p>\n

Physical Indicators<\/strong><\/h3>\n