{"id":804,"date":"2018-06-01T10:00:47","date_gmt":"2018-06-01T10:00:47","guid":{"rendered":"https:\/\/fnfdoc.com\/?p=804"},"modified":"2019-02-20T16:11:24","modified_gmt":"2019-02-20T16:11:24","slug":"myasthenia-gravis-causes-treatment","status":"publish","type":"post","link":"https:\/\/fnfdoc.com\/myasthenia-gravis-causes-treatment\/","title":{"rendered":"Myasthenia Gravis Causes And Treatment"},"content":{"rendered":"

Have you watched Snow White and the seven dwarves? The movie revolves around a lovely young princess who is rescued by seven dwarves dwelling in the wilderness. One of the dwarves in the Disney version, “The Sleepy Dwarf” has droopy eyelids not because he is sluggish or drowsy but due to the fact that he is loosely based on Walt Disney’s friend who had Myasthenia Gravis. Myasthenia Gravis is a rare autoimmune disorder that affects nearly all muscles of the human body. In Latin and Greek, it means ‘Grave Muscular Weakness.’ The more you use a muscle, the weaker it becomes. Also, stress and many other factors aggravate the condition. The disease has a reputation for being misunderstood or not understood at all. So we will take a moment to discuss the causes and effects of this paralyzing, deteriorating illness.<\/span><\/p>\n

What Causes Myasthenia Gravis?<\/span><\/h2>\n

Imagine waking up in the morning and not having the energy to get out of bed. Visualize that you feel drained without knowing why. Picture having to suffer surprising episodes of tingling and pain in your muscles. Imagine not being able to comb your hair or climb up a flight of stairs or laugh loudly. If the picture in your mind scares you then you can fathom the abysmal fear that a myasthenia patient lives in. And to think that the sole cause of all this trouble is an overactive immune system – well, so often it is our own wellwishers that screw us up.<\/span><\/p>\n

Autoantibodies Attack ACh Receptors<\/span><\/h3>\n

Myasthenia Gravis occurs because your immune system goes into the over-efficient super-man mode. It starts attacking your own body cells. In this manner, it releases antibodies that inhibit, block or attack acetylcholine receptors on the postsynaptic membrane. Thus, the acetylcholine after exiting the nerve ending fails to attach itself to the muscle membrane. Hence the voluntary muscles of the body become weakened and don’t respond to a mental command. So if you are chewing bubble gum and aim to direct the jaw muscles to contract and relax, they might just disappoint you. Why? Simply because the nerve impulse instructing them to perform the action of chewing wasn’t transmitted to the jaw muscles.<\/span><\/p>\n

Autoantibodies Inhibit Tyrosine Kinase<\/span><\/h3>\n

In addition to stopping the acetylcholine from attaching to the receptor site, some cells of the immune system inhibit the function of tyrosine kinase, a protein that acts as a receptor in muscles. Actually, the antibodies released by the immune system retard the functional capability of tyrosine kinase. This functional defect is directly linked to the development of MG in some patients.<\/span><\/p>\n

Role Of Thymus\u00a0Gland<\/span><\/h3>\n

The thymus gland is a component of the immune system, located just beneath your breastbone.<\/span><\/p>\n